Located at 506 South 1st Street in Immokalee, Seminole Casino Hotel Immokalee is easily accessible to all of Southwest Florida via I-75 and Southwest Florida International Airport is only a 45-minute drive from the casino. Located between Miami and Naples, north of Alligator Alley on Highway 846, it is five blocks south of Highway 29. Authorities said Martinez pulled over Shoulta and Riley near mile marker 48 of Alligator Alley, located in the tribe's reservation, on Aug. Speaking on the witness stand, Shoulta said. 801 reviews of Seminole Hard Rock Hotel & Casino 'I love coming here! It's got a variety of bars and clubs. And if you want a laugh then you should head to the improv club. There's a water and light show every weekend and if it's a family affair you're looking for they even have a zoo.